San Francisco 49ers vs. Los Angeles Rams Betting Lines & Preview | NFL Week 4

The San Francisco 49ers (1-2) host a NFC West clash against the Los Angeles Rams (2-1) on Monday, October 3, 2022 at Levi’s Stadium.

The 49ers are slight favorites (-2.5) in their game versus the Rams, with the over/under being 42.5 points. (On the moneyline, the 49ers are -144 and the Rams are +121.)

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Game Info, Betting Lines for San Francisco 49ers vs. Los Angeles Rams

• Game Day: Monday, October 3, 2022
• Game Time: 8:15 PM ET
• TV Channel: ESPN
• Location: Santa Clara, California
• Stadium: Levi’s Stadium

Betting Insights for 49ers

• The 49ers is 1-2-0 against the spread this season.
• In games they have played as at least 2.5-point favorites this season, the 49ers are 1-1 against the spread.
• None of the 49ers’ three games with a set total this season have gone over the point total.

Stats & Insights for 49ers

• The 49ers own the 23rd-ranked offense this year (323.7 yards per game), and they’ve been even better on defense, ranking second-best with only 227 yards allowed per game.
• While the 49ers rank fifth-worst in the NFL in scoring offense with 15.7 points per game, it’s been a different story on defense, as they rank third-best (12.3 points per game allowed).
• The 49ers have struggled in the passing game, ranking fourth-worst in the NFL (172.7 passing yards per game) this season. However, they rank best on the defensive side of the ball, giving up only 148.3 passing yards per game.
• The 49ers rank sixth in rushing yards this year (151 rushing yards per game), but they’ve been playing really well on defense, ranking fourth-best in the NFL with 78.7 rushing yards allowed per game.
• The 49ers rank 20th in third-down efficiency (35.7%) on offense and ninth in third-down conversion rate allowed (32.5%) on defense this year.
• The 49ers are gaining 5.4 yards per play on offense (22nd in the league), while featuring the best yards per play on defense in the NFL (4.3) this season.
• The 49ers have forced four total turnovers (12th in NFL) this season and have turned it over five times (19th in NFL) for a turnover margin of -1, 19th-ranked in the NFL.

49ers’ Best Players

• Jeff Wilson Jr.: 39 CAR / 181 YDS / 60.3 YPG / 0 TD / 7 REC / 58 YDS / 19.3 YPG / 0 TD
• Deebo Samuel: 17 CAR / 111 YDS / 37 YPG / 1 TD / 12 REC / 131 YDS / 43.7 YPG / 0 TD
• Brandon Aiyuk: 10 REC / 142 YDS / 47.3 YPG / 1 TD
• Jauan Jennings: 6 REC / 71 YDS / 23.7 YPG / 0 TD
• Nick Bosa: 11 TKL / 4 TFL / 4 SACK
• Dre Greenlaw: 23 TKL / 2 TFL
• Tashaun Gipson: 9 TKL / 1 INT / 1 PD

Betting Insights for Rams

• The Rams is 1-2-0 against the spread this season.
• The Rams have not yet covered the spread as underdogs of 2.5 points or more this year (0-1).
• In Rams three games with a set total, one has hit the over (33.3%).

Stats & Insights for Rams

• From an offensive standpoint, the Rams are accumulating 306.3 total yards per contest (24th-ranked). They rank 17th in the NFL on the other side of the ball (346.3 total yards given up per game).
• In terms of points scored the Rams rank 15th in the NFL (20.3 points per game), and they are 20th defensively (23.3 points allowed per contest).
• In terms of passing, the Rams rank 17th in the NFL (234 passing yards per game) and 23rd defensively (252.7 passing yards allowed per contest).
• The Rams’ running game has been sputtering, ranking third-worst in the NFL with 72.3 rushing yards per game. They have been more productive on defense, allowing 93.7 rushing yards per contest (10th-ranked).
• The Rams’ third-down offense has been paving the way for the team, as they rank fifth-best in the NFL with a 48.4% third-down conversion rate. In terms of defense, they are surrendering a 47.4% third-down rate, which ranks 26th.
• With 5.6 yards per play on offense, the Rams rank 14th in the NFL. On defense they rank 14th, surrendering 5.6 yards per play.
• After forcing seven turnovers (fourth in NFL) and turning the ball over seven times (28th in NFL) this season, the Rams own the 14th-ranked turnover margin of 0.

Best Players for Rams

• Matthew Stafford: 761 PASS YDS / 253.7 YPG / 72.5% / 4 TD / 5 INT
• Darrell Henderson: 27 CAR / 111 YDS / 37 YPG / 1 TD / 5 REC / 26 YDS / 8.7 YPG / 0 TD
• Cam Akers: 30 CAR / 105 YDS / 35 YPG / 1 TD / 2 REC / 18 YDS / 6 YPG / 0 TD
• Cooper Kupp: 28 REC / 280 YDS / 93.3 YPG / 3 TD
• Tyler Higbee: 16 REC / 171 YDS / 57 YPG / 0 TD
• Ben Skowronek: 10 REC / 107 YDS / 35.7 YPG / 0 TD
• Bobby Wagner: 23 TKL / 2 TFL / 2 SACK
• Ernest Jones: 24 TKL / 1 TFL
• Terrell Lewis: 8 TKL / 1 TFL / 1 SACK / 1 INT / 1 PD