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    The Tennessee Titans (0-1) visit the Buffalo Bills (1-0) at Highmark Stadium on Monday, September 19, 2022.

    The Bills are expected to win by double digits (currently -10) against the Titans. The over/under for this game is 49.5 points.

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    Game Info, Betting Lines for Buffalo Bills vs. Tennessee Titans

    • Game Day: Monday, September 19, 2022
    • Game Time: 7:15 PM ET
    • TV Channel: ESPN
    • Location: Orchard Park, New York
    • Stadium: Highmark Stadium
    Bills vs Titans Betting Information
    Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline
    Bills -10 -110 -110 49.5 -111 -109 -460 +351

    Betting Insights for Bills

    • The Bills won nine games against the spread last season, failing to cover or pushing eight times.
    • When playing as at least 10-point favorites last season, the Bills had an ATS record of 5-1-1.
    • Last season, eight of the Bills’ games went over the point total.

    Stats & Insights for Bills

    • The Bills racked up 7.6 more points per game (28.4) than the Titans allowed (20.8) last year.
    • The Bills were 9-2 against the spread and 11-2 overall last season when the team put up more than 20.8 points.
    • The Titans had a 7-5 record against the spread and a 9-3 record overall in games when they allowed less than 28.4 points last year.
    • The Bills averaged 52.1 more yards per game (381.9) than the Titans allowed per outing (329.8) last year.
    • In games that the Bills picked up over 329.8 yards last season, the team was 7-3 against the spread and 9-3 overall.
    • The Titans had a 6-5 record ATS and an 8-3 record overall when holding their opponents to less than 381.9 yards last year.
    • The Bills rushed for 129.9 yards per game last season, 45.3 more than the 84.6 the Titans allowed per contest.
    • When the Bills ran for over 84.6 yards last year, they had a 9-4 ATS record and an 11-4 overall record.
    • The Titans were 9-6 against the spread and 11-4 overall when holding opponents to less than 129.9 rushing yards last season.
    • Last year the Bills turned the ball over 22 times, while the Titans forced 22.

    Bills’ Best Players

    • Josh Allen: 4,407 PASS YDS / 259.2 YPG / 63.3% / 36 TD / 15 INT / 122 CAR / 763 RUSH YDS / 6 TD
    • Devin Singletary: 188 CAR / 870 YDS / 51.2 YPG / 7 TD / 40 REC / 228 YDS / 13.4 YPG / 1 TD
    • Stefon Diggs: 103 REC / 1,225 YDS / 72.1 YPG / 10 TD
    • Dawson Knox: 49 REC / 587 YDS / 39.1 YPG / 9 TD
    • Gabriel Davis: 35 REC / 549 YDS / 34.3 YPG / 6 TD
    • Von Miller: 50 TKL / 19 TFL / 9.5 SACK / 1 PD
    • Tremaine Edmunds: 108 TKL / 7 TFL / 1 INT / 4 PD
    • Jordan Poyer: 91 TKL / 8 TFL / 3 SACK / 5 INT / 9 PD

    Betting Insights for Titans

    • The Titans covered the spread 10 times in 17 games last season.
    • The Titans had eight of its 17 games go over the point total last year.

    Stats & Insights for Titans

    • Last season the Titans scored 7.6 more points per game (24.6) than the Bills gave up (17).
    • The Titans were 10-3 against the spread and 12-1 overall in games when they put up more than 17 points last year.
    • When the Bills limited opponents to fewer than 24.6 points last season, they had a 9-3 record against the spread and an 11-3 record overall.
    • The Titans racked up 342.5 yards per game last season, 69.3 more yards than the 273.2 the Bills gave up per contest.
    • In games that the Titans churned out more than 273.2 yards last season, the team was 8-5 against the spread and 9-4 overall.
    • In games the Bills held their opponents to less than 342.5 yards last season, they had an 8-3-1 record ATS and a 9-3 record overall.
    • Last season the Titans racked up 141.4 rushing yards per game, 31.6 more than the Bills allowed per outing (109.8).
    • The Titans had a 5-4 ATS record and a 6-3 overall record when the team ran for over 109.8 yards last season.
    • When the Bills limited their opponents to fewer than 141.4 rushing yards last season, they were 8-3-1 against the spread and 9-3 overall.
    • Last season the Titans had 25 turnovers, five fewer than the Bills had takeaways (30).

    Best Players for Titans

    • Ryan Tannehill: 3,734 PASS YDS / 219.6 YPG / 67.2% / 21 TD / 14 INT / 55 CAR / 270 RUSH YDS / 7 TD
    • Derrick Henry: 219 CAR / 937 YDS / 117.1 YPG / 10 TD / 18 REC / 154 YDS / 19.3 YPG / 0 TD
    • Dontrell Hilliard: 56 CAR / 350 YDS / 43.8 YPG / 2 TD / 19 REC / 87 YDS / 10.9 YPG / 0 TD
    • Robert Woods: 45 REC / 556 YDS / 61.8 YPG / 4 TD
    • Nick Westbrook-Ikhine: 38 REC / 476 YDS / 29.8 YPG / 4 TD
    • Austin Hooper: 38 REC / 345 YDS / 21.6 YPG / 3 TD
    • Denico Autry: 31 TKL / 10 TFL / 9 SACK / 6 PD
    • Zach Cunningham: 92 TKL / 7 TFL / 3 PD
    • Kevin Byard: 88 TKL / 1 TFL / 1 SACK / 5 INT / 13 PD
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