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    The San Francisco 49ers (3-2) visit the Atlanta Falcons (2-3) at Mercedes-Benz Stadium on Sunday, October 16, 2022.

    The 49ers are favored, but by less than a touchdown (-5.5), against the Falcons. The over/under for this matchup is 43 points.

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    Game Info, Betting Lines for San Francisco 49ers vs. Atlanta Falcons

    • Game Day: Sunday, October 16, 2022
    • Game Time: 1:00 PM ET
    • TV Channel: FOX
    • Location: Atlanta, Georgia
    • Stadium: Mercedes-Benz Stadium
    49ers vs Falcons Betting Information
    Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline
    49ers -5.5 -110 -111 43 -111 -110 -241 +196

    Betting Insights for 49ers

    • The 49ers have gone 3-2-0 ATS this season.
    • The 49ers have a 2-1 record against the spread in games they were favored by 5.5 points or more this season.
    • Out of the 49ers’ five games with a set total, one has hit the over (20%).

    Stats & Insights for 49ers

    • The 49ers rank 20th in total offense this year (339 yards per game), but they’ve been playing really well on defense, ranking best in the NFL with 249.2 yards allowed per game.
    • On defense, the 49ers have been a top-five unit, ranking best by surrendering only 12.2 points per game. They rank 16th on offense (21.6 points per game).
    • The 49ers rank 25th in passing yards this season (200.2 per game), but they’ve been shining on defense, ranking third-best in the NFL with 177.8 passing yards allowed per game.
    • On defense, the 49ers have been a top-five unit in terms of rushing yards, ranking second-best by allowing only 71.4 per game. They rank eighth on offense (138.8 rushing yards per game).
    • On the defensive side of the ball, the 49ers have been a top-five unit in terms of third-down efficiency, ranking third-best by surrendering a 30% third-down percentage. They rank 11th on offense (40.9% third-down conversion rate).
    • The 49ers have the best defense in the NFL in terms of yards per play allowed (4.5), while their offense is ranked 13th, putting up 5.8 per play.
    • The 49ers have forced seven total turnovers (13th in NFL) this season and have turned it over six times (10th in NFL) for a turnover margin of +1, ninth-ranked in the league.

    49ers’ Best Players

    • Jimmy Garoppolo: 857 PASS YDS / 171.4 YPG / 60.7% / 5 TD / 1 INT
    • Jeff Wilson Jr.: 74 CAR / 375 YDS / 75 YPG / 2 TD / 8 REC / 70 YDS / 14 YPG / 0 TD
    • Deebo Samuel: 21 CAR / 125 YDS / 25 YPG / 1 TD / 20 REC / 266 YDS / 53.2 YPG / 2 TD
    • Brandon Aiyuk: 17 REC / 237 YDS / 47.4 YPG / 1 TD
    • Jauan Jennings: 10 REC / 138 YDS / 27.6 YPG / 0 TD
    • Nick Bosa: 15 TKL / 6 TFL / 6 SACK
    • Dre Greenlaw: 49 TKL / 3 TFL
    • Talanoa Hufanga: 30 TKL / 5 TFL / 1 SACK / 2 INT / 5 PD

    Betting Insights for Falcons

    • The Falcons have put together a perfect 5-0-0 record against the spread this year.
    • In games this year in which they were an underdog by 5.5 points or more, the Falcons have a 3-0 record against the spread.
    • The Falcons have hit the over in three of their five games with a set total (60%).

    Stats & Insights for Falcons

    • The Falcons rank 25th with 331.4 total yards per game on offense, and they rank 27th with 393 total yards given up per game on defense.
    • The Falcons are generating 23.6 points per game on offense this season (10th-ranked). Meanwhile, they are surrendering 24.4 points per contest (21st-ranked) on defense.
    • The Falcons have lots of room to get better in the passing game, as they rank third-worst in passing yards per game (166.8) this season and fourth-worst in passing yards surrendered per game (278.2).
    • The Falcons’ run defense ranks 17th in the NFL with 114.8 rushing yards given up per game, but they’ve been carried by their offense, which ranks third-best by accumulating 164.6 rushing yards per game.
    • From an offensive angle, the Falcons are generating a 39.6% third-down conversion rate (16th-ranked). They rank 27th in the NFL on the other side of the ball (47.1% third-down rate allowed).
    • From an offensive perspective, the Falcons are putting up 5.9 yards per play (10th-ranked). They rank 20th in the NFL defensively (6 yards allowed per play).
    • The Falcons have registered seven forced turnovers (13th in NFL) and committed eight turnovers (22nd in NFL) this season for a -1 turnover margin that ranks 22nd in the NFL.

    Best Players for Falcons

    • Marcus Mariota: 926 PASS YDS / 185.2 YPG / 57.7% / 4 TD / 4 INT / 37 CAR / 156 RUSH YDS / 2 TD
    • Tyler Allgeier: 39 CAR / 184 YDS / 36.8 YPG / 0 TD / 2 REC / 25 YDS / 5 YPG / 0 TD
    • Drake London: 22 REC / 266 YDS / 53.2 YPG / 2 TD
    • Olamide Zaccheaus: 12 REC / 213 YDS / 42.6 YPG / 2 TD
    • Kyle Pitts: 10 REC / 150 YDS / 30 YPG / 0 TD
    • Grady Jarrett: 19 TKL / 5 TFL / 3.5 SACK
    • Mykal Walker: 44 TKL / 2 TFL / 1 SACK / 1 INT / 2 PD
    • Dee Alford: 13 TKL / 1 TFL / 1 INT / 2 PD
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