Star wide receiver Michael Mayer and the Notre Dame Fighting Irish (5-3) play the Clemson Tigers (8-0) on Saturday at 7:30 PM ET at Notre Dame Stadium.

The Tigers are the favorites (-3.5) in their game versus the Fighting Irish, with the over/under being 44.5 points. (On the moneyline, the Tigers are -178 and the Fighting Irish are +143.)

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Game Info and Betting Lines for Clemson vs. Notre Dame

  • Game Day: Saturday, November 5, 2022
  • Game Time: 7:30 PM ET
  • TV Channel: NBC
  • Location: South Bend, Indiana
  • Stadium: Notre Dame Stadium
Tigers vs Fighting Irish Betting Information
Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline
Tigers -3.5 -112 -110 44.5 -111 -110 -178 +143

Clemson Betting Insights

  • Notre Dame is 3-4-0 against the spread this year.
  • Notre Dame is a perfect 1-0 against the spread when an underdog by 3.5 points or more this year.
  • Notre Dame has hit the over in three of their seven games with a set total (42.9%).

Clemson Stats & Insights

  • Clemson is putting up 422.5 yards per game on offense (47th in the FBS), and rank 28th defensively, yielding 333.6 yards allowed per game.
  • Clemson has been a handful for opposing teams, as they rank top-25 in both scoring offense (19th-best with 37.1 points per game) and scoring defense (21st-best with 19.9 points allowed per game) this year.
  • From an offensive standpoint, Clemson ranks 71st in the FBS with 236.1 passing yards per game. Meanwhile, the defense ranks 86th in passing yards allowed per contest (244.3).
  • On the defensive side of the ball, Clemson has been a top-25 unit in terms of rushing yards, ranking seventh-best by giving up just 89.4 per game. The Tigers rank 40th on offense (186.4 rushing yards per game).
  • Offensively, Clemson has been a top-25 unit in terms of third-down efficiency, ranking 19th-best in the FBS by putting up a 49.2% third-down conversion rate. The defense ranks 48th on defense (35.9% third-down percentage allowed).
  • With 11 forced turnovers (73rd in the FBS) against nine turnovers committed (31st in the FBS), Clemson’s +2+2 turnover margin ranks 53rd in college football.

Clemson’s Best Players

  • D.J. Uiagalelei has been a dual threat for Clemson so far this season. He has 1,802 passing yards, completing 64.1% of his passes and tossing 17 touchdown passes and four interceptions this season. He’s rushed for 359 yards (44.9 ypg) on 89 carries with four rushing touchdowns.
  • Will Shipley has carried the ball 123 times for a team-high 739 yards on the ground and has found the end zone 10 times. He’s also tacked on 19 catches for 153 yards (19.1 per game).
  • Antonio Williams’ team-high 364 yards as a receiver have come on 29 catches (out of 35 targets) with two touchdowns.
  • Joseph Ngata has put together a 324-yard season so far with one touchdown, reeling in 20 passes on 35 targets.
  • Beaux Collins has been the target of 32 passes and racked up 18 catches for 290 yards, an average of 36.3 yards per contest. He’s found the end zone five times through the air this season.
  • Myles Murphy leads the team with 4.5 sacks, and also has three TFL and 20 tackles.
  • Clemson’s top-tackler, Trenton Simpson, has 34 tackles and 0.5 sacks this year.
  • R.J. Mickens has picked off a team-high two passes. He also has 20 tackles, one TFL, and two passes defended to his name.

Notre Dame Betting Insights

  • Notre Dame has gone 3-4-0 ATS this season.
  • When it has played as at least 3.5-point underdogs this season, Notre Dame is 1-0 against the spread.
  • The teams have hit the over in three of Notre Dame’s seven games with a set total.

Notre Dame Stats & Insights

  • With 383 total yards per game on the offensive side of the ball, Notre Dame ranks 78th in the FBS in 2022. Defensively, it ranks 27th, surrendering 333.5 total yards per game.
  • Notre Dame is putting up 28.4 points per contest on offense this season (69th-ranked). Meanwhile, it is surrendering 22.1 points per contest (40th-ranked) on defense.
  • In terms of passing, Notre Dame ranks 106th in the FBS (196.4 passing yards per game) and 37th defensively (204.9 passing yards allowed per contest).
  • Notre Dame ranks 39th in the FBS with 186.6 rushing yards per game on offense, and it ranks 46th with 128.6 rushing yards surrendered per game on defense.
  • With a 42% third-down conversion rate on offense, Notre Dame ranks 49th in the FBS. Defensively, it ranks 35th, surrendering a 33.7% third-down rate.
  • With five forced turnovers (129th in the FBS) and 11 turnovers committed (61st in the FBS) this season, Notre Dame ranks 100th in the FBS with a turnover margin of -6.

Notre Dame’s Best Players

  • Drew Pyne leads Notre Dame with 1,193 yards on 102-of-165 passing with 13 touchdowns compared to four interceptions this season. He has chipped in with 107 rushing yards (13.4 ypg) on 29 carries.
  • The team’s top rusher, Audric Estime, has carried the ball 99 times for 558 yards (69.8 per game) with eight touchdowns.
  • Logan Diggs has run for 431 yards across 95 carries, scoring one touchdown.
  • Mayer’s 580 receiving yards (72.5 yards per game) are a team high. He has 47 receptions on 76 targets with six touchdowns.
  • Lorenzo Styles Jr. has recorded 292 receiving yards (36.5 yards per game) and one touchdown on 24 receptions.
  • Jayden Thomas’ 10 catches (on 20 targets) have netted him 157 yards (19.6 ypg) and two touchdowns.
  • Isaiah Foskey leads the team with seven sacks, and also has six TFL and 29 tackles.
  • JD Bertrand is the team’s leading tackler this year. He’s collected 43 tackles, one TFL, and one sack.
  • Brandon Joseph has picked off a team-high one pass. He also has 27 tackles and one pass defended to his name.
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