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    The New York Giants (1-1) hit the road to match up against the San Francisco 49ers (2-0) at Levi’s Stadium on Thursday, September 21, 2023.

    The 49ers sported the sixth-ranked offense last year (26.5 points per game), and they were more effective defensively, ranking best with only 16.3 points allowed per game. From an offensive standpoint, the Giants ranked 18th in the NFL with 333.9 yards per game last season. Meanwhile, they ranked 25th in total defense (358.2 yards allowed per contest).

    49ers vs. Giants Picks

    Splash Inc. users project the 49ers will win straight up and also cover against the Giants, with 98.1% of users picking them to win and 66.9% picking them to cover the 10.5-point spread on Thursday.

    Game Info: 49ers vs. Giants

    • Game Day: Thursday, September 21, 2023
    • Game Time: 8:15 PM ET
    • TV Channel: Amazon Prime Video
    • Location: Santa Clara, California
    • Stadium: Levi’s Stadium

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    Before you wager on Thursday’s San Francisco-New York spread (San Francisco -10.5) or total (43 points), read the betting insights and trends below.

    Game Trends for 49ers

    • The 49ers won 11 games against the spread last season, failing to cover six times.
    • The 49ers won their only game last season when playing as at least 10.5-point favorites.
    • Last season, the combined scoring went over the point total nine times in 49ers games.

    Stats & Insights for 49ers

    • The 49ers racked up 4.7 more points per game (26.5) than the Giants surrendered (21.8) last year.
    • When the 49ers put up over 21.8 points last season, they were 9-3 against the spread and 11-1 overall.
    • When the Giants limited opponents to fewer than 26.5 points last season, they had a 11-1 record against the spread and a 9-2-1 record overall.
    • The 49ers racked up only 7.4 more yards per game (365.6) than the Giants allowed per outing (358.2) last season.
    • When the 49ers picked up more than 358.2 yards last year, the team was 7-3 against the spread and 9-1 overall.
    • The Giants had a -2 record ATS and a – record overall when holding their opponents to fewer than 365.6 yards last year.
    • Last season, the 49ers ran for just 5.4 fewer yards (138.8) than the Giants allowed per contest (144.2).
    • The 49ers had a 7-3 ATS record and a 9-1 overall record when the team ran for more than 144.2 yards last season.
    • When the Giants limited their opponents to less than 138.8 rushing yards last season, they were -1 against the spread and – overall.
    • The 49ers had 17 giveaways last year, while the Giants had 19 takeaways.

    Best Players for 49ers

    • Brock Purdy: 1,374 PASS YDS / 152.7 YPG / 67.1% / 13 TD / 4 INT
    • Christian McCaffrey: 244 CAR / 1,139 YDS / 67 YPG / 8 TD / 85 REC / 741 YDS / 43.6 YPG / 5 TD
    • Elijah Mitchell: 45 CAR / 279 YDS / 55.8 YPG / 2 TD / 3 REC / 7 YDS / 1.4 YPG / 0 TD
    • Brandon Aiyuk: 78 REC / 1,015 YDS / 59.7 YPG / 8 TD
    • George Kittle: 60 REC / 765 YDS / 51 YPG / 11 TD
    • Fred Warner: 130 TKL / 3 TFL / 2 SACK / 1 INT / 10 PD

    Game Trends for Giants

    • The Giants beat the spread 13 times in 17 games last season.
    • The Giants covered every time (1-0) as underdogs of 10.5 points or greater last year.
    • Last year, seven of the Giants’ 17 games went over the point total.

    Stats & Insights for Giants

    • The Giants scored 5.2 more points per game (21.5) than the 49ers surrendered (16.3) last season.
    • When the Giants recorded over 16.3 points last season, they were 12-2 against the spread and 9-4-1 overall.
    • When the 49ers limited opponents to less than 21.5 points last season, they had a 11-3 record against the spread and a 12-2 record overall.
    • The Giants collected 333.9 yards per game last season, 33.3 more yards than the 300.6 the 49ers allowed per contest.
    • In games that the Giants amassed over 300.6 yards last season, the team was 8-3 against the spread and 6-4-1 overall.
    • In games the 49ers held their opponents to less than 333.9 yards last season, they had a -4 record ATS and a – record overall.
    • Last season the Giants racked up 148.2 yards per game on the ground, 70.5 more than the 49ers allowed per contest (77.7).
    • Last year the Giants had a 13-4 ATS record and a 9-7-1 overall record in games the team ran for more than 77.7 yards.
    • The 49ers were -5 against the spread and – overall when holding opponents to fewer than 148.2 rushing yards last season.
    • The Giants had 16 giveaways last year, while the 49ers had 30 takeaways.

    Best Players for Giants

    • Daniel Jones: 3,205 PASS YDS / 200.3 YPG / 67.2% / 15 TD / 5 INT / 120 CAR / 708 RUSH YDS / 7 TD
    • Saquon Barkley: 295 CAR / 1,312 YDS / 82 YPG / 10 TD / 57 REC / 338 YDS / 21.1 YPG / 0 TD
    • Darius Slayton: 46 REC / 724 YDS / 55.7 YPG / 2 TD
    • Parris Campbell: 63 REC / 623 YDS / 36.6 YPG / 3 TD
    • Isaiah Hodgins: 37 REC / 392 YDS / 43.6 YPG / 4 TD
    • Bobby Okereke: 149 TKL / 6 TFL / 5 PD
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