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    The San Francisco 49ers (3-0) head into a matchup with the Arizona Cardinals (1-2) on Sunday, October 1, 2023 at Levi’s Stadium on a three-game winning streak.

    The 49ers fired on all cylinders last season, as they ranked fifth-best in total offense (365.6 yards per game) and best in total defense (300.6 yards allowed per game). The Cardinals had the 21st-ranked scoring offense last season (20 points per game), and they were less effective on defense, ranking second-worst with 26.4 points allowed per game.

    49ers vs. Cardinals Picks

    At the moment, 97.3% of Splash Inc. users are picking the 49ers to win and 66.7% expect them to cover the 14-point spread as well against the Cardinals on Sunday.

    Game Info: 49ers vs. Cardinals

    • Game Day: Sunday, October 1, 2023
    • Game Time: 4:25 PM ET
    • TV Channel: FOX
    • Location: Santa Clara, California
    • Stadium: Levi’s Stadium

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    If you are planning on making a wager on San Francisco-Arizona outing (in which San Francisco is a 14-point favorite and the total has been set at 44 points), keep reading for a few betting insights and trends for Sunday’s game.

    Game Trends for 49ers

    • The 49ers put together an 11-6-0 ATS record last year.
    • The 49ers won their only game last season when playing as at least 14-point favorites.
    • A total of nine of the 49ers’ games last season hit the over.

    Stats & Insights for 49ers

    • The 49ers put up just 0.1 more points per game (26.5) than the Cardinals gave up (26.4) last season.
    • The 49ers were 8-1 against the spread and 9-0 overall last season when the team notched more than 26.4 points.
    • Last season the Cardinals had a 7-3 record against the spread and a 3-7 record overall in games when they held opponents to fewer than 26.5 points.
    • The 49ers collected only 16.7 more yards per game (365.6) than the Cardinals allowed per outing (348.9) last season.
    • In games that the 49ers churned out more than 348.9 yards last season, the team was 8-3 against the spread and 10-1 overall.
    • When the Cardinals kept their opponents to less than 365.6 yards last year, they had a -5 record ATS and a – record overall.
    • Last year the 49ers rushed for 20.2 more yards per game (138.8) than the Cardinals allowed per outing (118.6).
    • Last year the 49ers had a 8-3 ATS record and a 10-1 overall record in games the team rushed for more than 118.6 yards.
    • Last season, the Cardinals were -4 against the spread and – overall when holding opponents to less than 138.8 rushing yards.
    • Last year the 49ers had 17 turnovers, three fewer than the Cardinals had takeaways (20).

    Best Players for 49ers

    • Brock Purdy: 1,374 PASS YDS / 152.7 YPG / 67.1% / 13 TD / 4 INT
    • Christian McCaffrey: 244 CAR / 1,139 YDS / 67 YPG / 8 TD / 85 REC / 741 YDS / 43.6 YPG / 5 TD
    • Elijah Mitchell: 45 CAR / 279 YDS / 55.8 YPG / 2 TD / 3 REC / 7 YDS / 1.4 YPG / 0 TD
    • Brandon Aiyuk: 78 REC / 1,015 YDS / 59.7 YPG / 8 TD
    • George Kittle: 60 REC / 765 YDS / 51 YPG / 11 TD
    • Fred Warner: 130 TKL / 3 TFL / 2 SACK / 1 INT / 10 PD

    Game Trends for Cardinals

    • Cardinals posted a 8-9-0 record against the spread last season.
    • The Cardinals had no wins ATS (0-1) as underdogs of 14 points or more last year.
    • Out of the 17 Cardinals’ games last year, 10 went over the total.

    Stats & Insights for Cardinals

    • The Cardinals put up 20 points per game last season, 3.7 more than the 49ers allowed (16.3).
    • The Cardinals were 7-3 against the spread and 4-6 overall in games when they scored over 16.3 points last season.
    • When the 49ers limited opponents to fewer than 20 points last season, they had a 10-3 record against the spread and a 11-2 record overall.
    • The Cardinals averaged 323.5 yards per game last year, 22.9 more yards than the 300.6 the 49ers gave up per outing.
    • When the Cardinals picked up over 300.6 yards last season, the team was 7-5 against the spread and 3-9 overall.
    • When the 49ers kept their opponents to fewer than 323.5 yards last season, they had a -4 record ATS and a – record overall.
    • Last season the Cardinals rushed for 32.5 more yards per game (110.2) than the 49ers allowed per outing (77.7).
    • Last year the Cardinals had a 8-5 ATS record and a 4-9 overall record in games the team ran for over 77.7 yards.
    • The 49ers were -3 against the spread and – overall when holding opponents to fewer than 110.2 rushing yards last season.
    • The Cardinals turned the ball over 25 times last season, five fewer times than the 49ers forced turnovers (30).

    Best Players for Cardinals

    • James Conner: 183 CAR / 782 YDS / 60.2 YPG / 7 TD / 46 REC / 300 YDS / 23.1 YPG / 1 TD
    • Keaontay Ingram: 27 CAR / 60 YDS / 5.5 YPG / 1 TD / 4 REC / 21 YDS / 1.9 YPG / 0 TD
    • Marquise Brown: 67 REC / 709 YDS / 59.1 YPG / 3 TD
    • Greg Dortch: 52 REC / 467 YDS / 29.2 YPG / 2 TD
    • Rondale Moore: 41 REC / 414 YDS / 51.8 YPG / 1 TD
    • Kyzir White: 110 TKL / 3 TFL / 1.5 SACK / 7 PD
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