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    The San Francisco 49ers (3-0) bring a three-game winning streak into a meeting against the Arizona Cardinals (1-2) on Sunday, October 1, 2023 at Levi’s Stadium.

    The 49ers have been a handful for opposing teams, as they rank top-five in both total offense (fourth-best with 399 yards per game) and total defense (third-best with 258.3 yards allowed per game) this season. The Cardinals rank 18th with 329.7 total yards per contest on offense, and they rank 26th with 367.7 total yards allowed per game on defense.

    49ers vs. Cardinals Picks

    Splash Inc. users think the Cardinals will win straight up as underdogs and cover against the 49ers, with 1.8% of users picking them to win and 51.5% picking them to cover the 14-point spread on Sunday.

    Game Info: 49ers vs. Cardinals

    • Game Day: Sunday, October 1, 2023
    • Game Time: 4:25 PM ET
    • TV Channel: FOX
    • Location: Santa Clara, California
    • Stadium: Levi’s Stadium

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    Take a look at the betting trends and insights below before making a wager on Sunday’s San Francisco-Arizona spread (San Francisco -14) or total (43.5 points).

    Game Trends for 49ers

    • The 49ers are 2-1-0 against the spread this season.
    • The 49ers have combined with their opponent to go over in one of three games with a set total (33.3%).

    Stats & Insights for 49ers

    • The 49ers have been finding success on both offense and defense, ranking fourth-best in total offense (399 yards per game) and third-best in total defense (258.3 yards allowed per game).
    • The 49ers have been finding success on both offense and defense, ranking third-best in scoring offense (30 points per game) and fifth-best in scoring defense (14 points allowed per game).
    • The 49ers rank 10th in pass offense (236.3 passing yards per game) and 14th in pass defense (205.3 passing yards allowed per game) this year.
    • The 49ers have been clicking on all fronts in the running game this year, as they rank third-best in rushing offense (162.7 rushing yards per game) and third-best in rushing defense (53 rushing yards allowed per game).
    • The 49ers rank 10th in third-down efficiency (44.7%) on offense and 15th in third-down conversion rate allowed (36.6%) on defense this season.
    • The 49ers have been a tough opponent for opposing teams in terms of yards per play, as they rank top-five in both offensive yards per play (fourth-best with 6.2) and yards per play allowed on defense (second-best at 4.5) this year.
    • With five forced turnovers (seventh in NFL) against one turnover committed (first in NFL), the 49ers’ +4 turnover margin is the third-best in the league.

    Best Players for 49ers

    • Brock Purdy: 736 PASS YDS / 245.3 YPG / 67% / 4 TD / 0 INT
    • Christian McCaffrey: 60 CAR / 353 YDS / 117.7 YPG / 3 TD / 11 REC / 70 YDS / 23.3 YPG / 0 TD
    • Elijah Mitchell: 16 CAR / 52 YDS / 26 YPG / 0 TD
    • Deebo Samuel: 17 REC / 247 YDS / 82.3 YPG / 1 TD
    • Brandon Aiyuk: 11 REC / 172 YDS / 86 YPG / 2 TD
    • George Kittle: 13 REC / 139 YDS / 46.3 YPG / 0 TD
    • Deommodore Lenoir: 25 TKL / 1 INT / 1 PD

    Game Trends for Cardinals

    • The Cardinals have put together a perfect 3-0-0 record against the spread this season.
    • Two of the Cardinals’ three games with a set total have hit the over (66.7%).

    Stats & Insights for Cardinals

    • The Cardinals are posting 329.7 total yards per game on offense this season (18th-ranked). Meanwhile, they are giving up 367.7 total yards per game (26th-ranked).
    • From an offensive perspective, the Cardinals are putting up 24 points per contest (13th-ranked). They rank 15th in the NFL on the other side of the ball (22.3 points given up per game).
    • The Cardinals rank 27th in the NFL with 173.3 passing yards per game on offense, and they rank 21st with 233 passing yards given up per contest on the defensive side of the ball.
    • From an offensive angle, the Cardinals are putting up 156.3 rushing yards per contest (sixth-ranked). They rank 26th in the NFL defensively (134.7 rushing yards given up per game).
    • The Cardinals’ defense has been bottom-five on third down this season, surrendering a 50% third-down conversion percentage, which ranks fourth-worst in the NFL. On the offensive side of the ball, they rank 19th with a 50% third-down rate.
    • The Cardinals’ offense has been excelling in terms of yards per play, compiling 6 (fifth-best) this season. Defensively, they rank 21st by allowing 5.7 yards per play.
    • The Cardinals have recorded five forced turnovers (seventh in NFL) and committed two turnovers (fifth in NFL) this season for a +3 turnover margin that ranks seventh in the NFL.

    Best Players for Cardinals

    • James Conner: 51 CAR / 266 YDS / 88.7 YPG / 2 TD / 7 REC / 26 YDS / 8.7 YPG / 0 TD
    • Joshua Dobbs: 12 CAR / 93 YDS / 31 YPG / 1 TD
    • Michael Wilson: 7 REC / 161 YDS / 53.7 YPG / 0 TD
    • Marquise Brown: 14 REC / 143 YDS / 47.7 YPG / 2 TD
    • Zach Ertz: 14 REC / 83 YDS / 27.7 YPG / 0 TD
    • Kyzir White: 30 TKL / 3 TFL / 1 SACK / 1 INT / 1 PD
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