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    The San Francisco 49ers (4-4) square off against the Los Angeles Chargers (5-3) at Levi’s Stadium on Sunday, November 13, 2022.

    The Chargers are expected to lose by at least a touchdown (currently +7) against the 49ers (with an over/under of 46.5 points).

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    Game Info, Betting Lines for San Francisco 49ers vs. Los Angeles Chargers

    • Game Day: Sunday, November 13, 2022
    • Game Time: 8:20 PM ET
    • TV Channel: NBC
    • Location: Santa Clara, California
    • Stadium: Levi’s Stadium
    49ers vs Chargers Betting Information
    Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline
    49ers -7 -109 -111 46.5 -111 -110 -304 +243

    Betting Insights for 49ers

    • So far this season, the 49ers have put together a 4-4-0 record against the spread.
    • In games they have played as at least 7-point favorites this season, the 49ers are 1-0 against the spread.
    • The teams have hit the over in three of the 49ers’ eight games with a set total.

    Stats & Insights for 49ers

    • The 49ers rank 13th in total offense this year (356.6 yards per game), but they’ve been playing really well on the defensive side of the ball, ranking best in the NFL with 285.9 yards allowed per game.
    • The 49ers are totaling 22 points per game on offense this year (19th in NFL), and they are allowing 18.4 points per game (sixth) on defense.
    • The 49ers are totaling 237.1 passing yards per game offensively this year (11th in NFL), and they are allowing 199.3 passing yards per game (eighth) on the defensive side of the ball.
    • The 49ers sport the 15th-ranked offense this season in terms of rushing yards (119.5 per game), and they’ve been better defensively, ranking best with just 86.6 rushing yards allowed per game.
    • On offense, the 49ers rank seventh in the NFL with a 44.3% third-down percentage. Meanwhile, they rank 20th in third-down percentage allowed (41.5%).
    • The 49ers are gaining 6.1 yards per play on offense (seventh in the league), while featuring the second-best yards per play on defense in the NFL (5.1) this season.
    • With nine forced turnovers (19th in NFL) against 12 turnovers committed (17th in NFL), the 49ers’ -3 turnover margin ranks 22nd in the NFL.

    49ers’ Best Players

    • Jimmy Garoppolo: 1,691 PASS YDS / 241.6 YPG / 66.7% / 11 TD / 4 INT
    • Christian McCaffrey: 111 CAR / 525 YDS / 65.6 YPG / 3 TD / 43 REC / 356 YDS / 44.5 YPG / 2 TD
    • Deebo Samuel: 24 CAR / 138 YDS / 19.7 YPG / 1 TD / 32 REC / 387 YDS / 55.3 YPG / 2 TD
    • Brandon Aiyuk: 38 REC / 483 YDS / 60.4 YPG / 4 TD
    • Nick Bosa: 23 TKL / 8 TFL / 8.5 SACK
    • Fred Warner: 62 TKL / 1 TFL / 1 SACK / 3 PD
    • Talanoa Hufanga: 48 TKL / 5 TFL / 1 SACK / 3 INT / 6 PD

    Betting Insights for Chargers

    • The Chargers have gone 5-3-0 ATS this year.
    • Out of the Chargers’ eight games with a set total, four have hit the over (50%).

    Stats & Insights for Chargers

    • The Chargers rank ninth with 364.3 total yards per game on offense, and they rank 20th with 352.3 total yards surrendered per contest on defense.
    • The Chargers’ defense has been a bottom-five unit in scoring defense this season, conceding 25.8 points per game, which ranks third-worst in the NFL. On offense, they rank 13th with 23 points per contest.
    • The Chargers’ pass offense has been dominant, piling up 275.1 passing yards per game (fourth-best) this season. On defense, they rank 13th by allowing 206.8 passing yards per game.
    • In terms of rushing, this season has been difficult for the Chargers on both offense and defense, as they are averaging just 89.1 rushing yards per contest (fifth-worst) and surrendering 145.5 rushing yards per game (fourth-worst).
    • With a 41.8% third-down conversion rate on offense, the Chargers rank 13th in the NFL. Defensively, they rank 20th, allowing a 41.5% third-down rate.
    • The Chargers rank 23rd in yards per play (5.4), but they’ve been less productive defensively, fourth-worst in the NFL with 6.2 yards surrendered per play.
    • At +2, the Chargers have the ninth-ranked turnover margin in the NFL, with 11 forced turnovers (14th in NFL) and nine turnovers committed (seventh in NFL).

    Best Players for Chargers

    • Justin Herbert: 2,254 PASS YDS / 281.8 YPG / 66.4% / 13 TD / 5 INT
    • Austin Ekeler: 98 CAR / 427 YDS / 53.4 YPG / 6 TD / 60 REC / 381 YDS / 47.6 YPG / 4 TD
    • Sony Michel: 34 CAR / 103 YDS / 12.9 YPG / 0 TD / 9 REC / 53 YDS / 6.6 YPG / 0 TD
    • Mike Williams: 37 REC / 495 YDS / 70.7 YPG / 3 TD
    • Josh Palmer: 34 REC / 346 YDS / 49.4 YPG / 1 TD
    • Khalil Mack: 27 TKL / 7 TFL / 6 SACK / 1 PD
    • Derwin James: 72 TKL / 4 TFL / 3 SACK / 3 PD
    • Bryce Callahan: 22 TKL / 2 TFL / 2 INT / 5 PD
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