Chicago White Sox vs. Cleveland Guardians MLB Betting Preview | September 21

Steven Kwan leads the Cleveland Guardians (81-67) into a matchup with the Chicago White Sox (76-72) after his four-hit showing in a 10-7 win over the White Sox. The White Sox are favored on the moneyline (-130) in this game against the underdog Guardians (+110), which begins at 8:10 PM ET on Wednesday. Chicago’s Lance Lynn and Cleveland’s Triston McKenzie pitch first for their squads in this matchup.

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Game Info, Betting Lines for White Sox vs. Guardians

• Game Day: Wednesday, September 21, 2022
• Game Time: 8:10 PM ET
• Location: Chicago, Illinois
• Stadium: Guaranteed Rate Field

White Sox Stats & Trends

White Sox Batting

• The White Sox average 0.9 home runs per game to rank 22nd in MLB action with 138 total home runs .
• The White Sox have the second-best batting average in the league (.261).
• The White Sox are 13th in baseball with an on-base percentage of .316.
• The White Sox strike out 7.8 times per game, the seventh-fewest average in the league.
• The White Sox average 0.9 homers per game when playing at home this season (69 total in home contests).
• The White Sox have a .386 slugging percentage and are averaging 2.5 extra-base hits per game at home.
• The club averages 8.6 hits per game and is batting .255 at home this season.

White Sox Key Batters

• Jose Abreu leads Chicago in OBP (.383), slugging percentage (.451) and OPS (.834) this season.
• Among qualifying hitters in the majors, Abreu is seventh in batting average, eighth in on-base percentage, and 50th in slugging.
• Abreu hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .273 with two doubles, a walk and five RBI.
• Andrew Vaughn leads Chicago in total hits (135) this season while batting .286 with 46 extra-base hits.
• Among qualifying hitters, Vaughn’s batting average places him 24th, his on-base percentage 55th, and his slugging percentage 41st.
• Elvis Andrus has collected 123 base hits, an OBP of .315 and a slugging percentage of .411 this season.
• Andrus brings a seven-game hitting streak into this game. In his last 10 outings he is batting .364 with three doubles, two home runs, four walks and seven RBI.
• A.J. Pollock is batting .246 with a .292 OBP and 54 RBI for Chicago this season.
• Pollock has hit safely in three straight games. During his last five outings he is batting .227 with two home runs and six RBI.

Guardians Stats & Trends

Guardians Batting

• The Guardians’ 116 home runs rank 29th in MLB this season.
• The Guardians’ .252 batting average is among the best in baseball, ranking 10th in MLB.
• The Guardians have an on-base percentage of .315 this season, which ranks 15th in the league.
• No team has fewer strikeouts this season than the Guardians, who have struck out only 6.8 times per game on average.
• They’ve hit 71 homers, an average of 0.9 per game, in 76 road contests this season.
• They have a team slugging percentage of .397 in away games this season with 225 extra-base hits.
• They are averaging 9.0 base hits per game and batting .255 on the road this season.

Guardians Key Batters

• Jose Ramirez has totaled 153 hits, a team-high for the Guardians.
• Including all the qualifying hitters in MLB, Ramirez’s batting average ranks 32nd, his on-base percentage ranks 27th, and he is 10th in slugging.
• Ramirez takes a two-game hitting streak into this matchup. In his last five games he is batting .238 with a home run, five walks and four RBI.
• Kwan has a .373 OBP to lead his team.
• Kwan is currently 16th in batting average, 13th in on-base percentage and 108th in slugging percentage among all qualifying batters.
• Amed Rosario has accumulated a slugging percentage of .405, a team-best for the Guardians.
• Andres Gimenez is hitting .297 with 25 doubles, three triples, 16 home runs and 31 walks.

White Sox vs. Guardians Probable Pitchers